Transgenic Animals Applications And Examples

Transgenesis is the process by which mixing up of genes takes place.

Transgenic animals applications and examples. Transgenic animals are specially designed to study the role of genes in the development of certain diseases. Cohen and Herbert Boyer. Moreover in order to devise a cure for these diseases the transgenic animals are used as model organisms.

Applications Transgenic models for Alzheimer disease amyotrophic lateral sclerosis Huntington disease arthritis muscular dystrophy tumorigenesis hypertension neurodegenerative disorders endocrinological dysfunction coronary disease etc. Transgenic expression is not only used to breed animals which have specific traits but also to breed animals that are lacking specific genes This technique is called as knockout or gene targeting. Use of transgenic animals will provide solutions for drug research xenotransplantation clinical trials and will prove to be a new insight in drug development.

The term genetic engineering is used to describe the process Transgenic animal models of human disease can be useful for preclinical drug testing. The application of transgenic animals showed that within the next five to eight years genetically modified animals will play a significant and important role in the biomedical field in particular via the production of valuable pharmaceutical proteins and the supply of xenografts. These bacteria contained genetic information from a variety of different species.

For example most common laboratory animals are mice and rabbits. The foreign gene is constructed using recombinant DNA methodology. Pluripotent stem cell technology.

Transgenic animals are those that have been genetically modified. Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Transgenic technology has led to the development of fishes live stock and other animals with altered genetic profiles which.

With increasing knowledge about the genetics and improvements in the transgenetic technology numerous useful applications like biologically safe new-generation drugs based on human regulatory proteins are being developedVarious aspects of concern in the coming years are the regulatory guidelines ethical issues and patents related to the use of transgenic animals. The first genetically modified organism was a bacteria created in 1973 by Stanley N. Transgenic animals are animals that have been genetically transformed by splicing and inserting foreign animal or human genes into their chromosomes.